Roger Federer will make his comeback at the Laver Cup in September before playing the Swiss Indoors Basel event in his home city.
It means the legendary 20-time grand slam winner is set to miss all four majors this year.
The eight-time Wimbledon champion will turn 41 in August, and it remains to be seen whether the two events turn out to be farewell tournaments before he retires.
Federer has battled knee trouble over the past two years and has barely featured on the ATP Tour, with his most recent appearance coming at Wimbledon last year, where he was beaten in the quarter-finals by Hubert Hurkacz, a straight-sets defeat that culminated in a 6-0 third set.
The Swiss great has undergone surgery in an effort to finish his career on his own terms.
News of his comeback plans were announced by the Swiss Indoors organisers, who issued a statement that said: "Ten-time singles champion and hometown hero Roger Federer has announced his comeback to the stadium at St Jakobshalle. The Swiss all-time great has confirmed his initial agenda will include the Laver Cup in London followed by the Swiss Indoors in Basel."
Responding to the announcement, Federer posted on Instagram: "Looking forward to playing back home."
The Laver Cup takes place in London from September 23 to 25, and the Swiss Indoors Basel runs from October 24 to 30.
Federer will play his opening match at the latter on Tuesday, October 25, the organisers said.
"The worldwide interest in the return of the hometown hero and 20-time grand slam champion to the ATP Tour is expected to be tremendous," the Swiss Indoors statement added.
Federer for a long time held the record for the most grand slam singles titles won by a man; however, he has been joined on 20 by Novak Djokovic, and Rafael Nadal moved out on his own with 21 by triumphing at the Australian Open this year.