Carlos Alcaraz was made to come from a set down but finally overcame Nicola Kuhn in the first round of the Hamburg European Open.

The highly rated Spanish teenager eventually downed the German wildcard 3-6 6-1 7-6 (7-3).

Kuhn, ranked 259 in the world, was aggressive early on against Alcaraz, and was rewarded with the first set.

But the 19-year-old – playing as top seed in an ATP Tour event for the first time – rallied to ease through the second set, before being made to work much harder to clinch the win on a tie-break.

Alcaraz will now play Filip Krajinovic in the second round after the Serbian also won in a third-set tie-break against Sebastian Baez 6-1 4-6 7-6 (8-6).

Three seeded players crashed out on Tuesday in straight sets, with third favourite Diego Schwartzman losing against Emil Ruusuvuori 7-5 6-4, sixth seed Nikoloz Basilashvili beaten by Aslan Karatsev 6-4 6-0, and eighth seed Holger Rune going down 7-6 (10-8) 7-5 to Tallon Griekspoor.

Fourth seed Pablo Carreno Busta eased through against Luca Nardi 6-2 6-1, while there were also wins for Fabio Fognini, who sealed his 400th career victory, as well as Daniel Elahi Galan, Borna Coric and Francisco Cerundolo.

At the Swiss Open in Gstaad, sixth seed Cristian Garin lost 6-3 6-4 to Yannick Hanfmann and seventh favourite Hugo Gaston fell to Dominic Thiem despite winning the first set, losing 1-6 6-1 7-6 (9-7).

Elsewhere, Frenchman Richard Gasquet beat Roberto Carballes Baena 7-5 6-4, while his compatriot Benoit Paire retired hurt when a set and a break down against Elias Ymer.

A tight game between Swiss pair Dominic Stricker and Marc-Andrea Huesler saw the former prevail 6-7 (2-7) 7-6 (7-2) 6-4, and an all-Spanish affair was similarly close as Jaume Munar defeated Bernabe Zapata Miralles 6-3 3-6 7-5.

There were also wins for qualifiers Juan Pablo Varillas and Nicolas Jarry against Lorenzo Sonego and Thiago Monteiro respectively.