Tottenham were stunned by a controversial stoppage-time penalty from James Ward-Prowse as a 3-3 draw at rock-bottom Southampton saw Spurs' grip on fourth loosened.
Antonio Conte's men appeared to be heading third in the Premier League, providing a fine response to Newcastle United putting pressure on them a day earlier, but Saints battled back from 3-1 down to rescue a point.
Pedro Porro's first Premier League goal put Spurs ahead at the end of a stop-start first half, before Saints levelled through Che Adams early in the second.
Harry Kane and Ivan Perisic then seemed to have put the game beyond Saints, but Theo Walcott earned them a lifeline and Ward-Prowse's emphatic late spot-kick left Spurs reeling.
