Arjen Robben lasted just 30 minutes on his Eredivisie comeback as Groningen went down 3-1 to PSV.
Robben – making his first appearance in the Dutch top flight in over 16 years – was named in Groningen's starting XI for Sunday's clash against another of his former sides.
The ex-Real Madrid and Chelsea winger announced his retirement after leaving Bayern Munich in 2019, but signed with his boyhood club for the 2020-21 season.
However, the 36-year-old was on the pitch for half-an-hour before he trudged off with what appeared to be a hamstring problem.
Rust! Groningen kijkt tegen een achterstand aan door een goal van Gakpo, gemaakt na 34 minuten.— FC Groningen (@fcgroningen) September 13, 2020
Arjen Robben moest het veld na een half uur spelen geblesseerd verlaten en is vervangen door Suslov.
PSV took the lead four minutes later – Cody Gakpo putting the visitors ahead with a crisp finish.
Tomas Suslov equalised shortly after the break, yet Donyell Malen, who later missed a penalty, restored the advantage before Gakpo rounded off the win for PSV.