Tottenham lost Lucas Moura and Steven Bergwijn to injury as they played out a 2-2 draw with Ligue 1 side Rennes in Thursday's opening Europa Conference League match.
Lucas played a big part in Tottenham's opener, which was credited as a Loic Bade own goal, before having to make way following a poor challenge from Flavien Tait.
It was Tait who had earlier equalised for Rennes with a curled finish at an atmospheric Roazhon Park, shortly before Bergwijn was withdrawn with an apparent ankle issue.
Gaetan Laborde completed the turnaround 19 minutes from time, only for substitute Pierre-Emile Hojbjerg to quickly hit back and earn Spurs a point in the Group G clash.
The points are shared in Rennes. pic.twitter.com/RswBjW37IG— Tottenham Hotspur (@SpursOfficial) September 16, 2021
Tanguy Ndombele was brought into the Tottenham side for his first appearance under Nuno Espirito Santo and played a huge part in the opening goal with 11 minutes played.
The Frenchman kept the ball in play with a fancy backheeled pass in a swift move that culminated in Lucas' attempted cross hitting Bade's boot and wrong-footing Romain Salin.
Serhou Guirassy then had a shot saved by Pierluigi Gollini but exchanged passes with Tait soon after for his team-mate to curl one into the bottom-right corner for the equaliser.
That ended Rennes' 212-minute wait for a goal and the hosts spurned a big chance to edge in front before half-time when Kamaldeen Sulemana headed wide from close range.
The second half had a disrupted feel to it following a number of fouls, one of which led to Lucas' injury, with the Spurs attacker unable to run off the damage.
That all changed when Laborde converted a rebound after Gollini pushed Sulemana's shot into his path, but it took Nuno's side just five minutes to respond through Hojbjerg's poked finish from close range to ensure the points were shared.