Manchester United lost further ground to Premier League leaders Manchester City as they played out a 0-0 draw with Chelsea at Stamford Bridge on Sunday.
The Red Devils are now 12 points behind Pep Guardiola's seemingly unstoppable side, who are well on their way to a third title in four seasons.
Elsewhere, Liverpool returned to winning ways against Sheffield United and Arsenal came from behind to beat Leicester City at the King Power Stadium.
A Gareth Bale-inspired Tottenham cruised past Burnley 4-0, while Crystal Palace and Fulham played out a dour 0-0 draw.
Another twist in the bout for the top 4 pic.twitter.com/SQ3NyfWbdr— Premier League (@premierleague) February 28, 2021
Chelsea 0-0 Manchester United: Red Devils' 'big six' struggles continue
While this result stretched United's unbeaten away run in the league to a whopping 20 matches – the joint-fifth-longest run in top-flight history – there was still a sense of disappointment at full-time.
Ole Gunnar Solskjaer's side have now failed to score in their last six league meetings with Arsenal, Chelsea, Liverpool, Manchester City or Tottenham, with each of their last four such matches finishing goalless.
This fixture has now finished 0-0 in both matches in a single league campaign for just the second time, the other occasion coming back in 1921-22.
It marked the first time Chelsea have drawn 0-0 against an opponent home and away in the Premier League in the same season for the first time since 2008-09 against Everton, while United last did so against Aston Villa in 1996-97.
Thomas Tuchel can at least toast becoming just the second coach to not concede a single goal in his first four home matches in the Premier League after Brendan Rodgers in 2011-12 with Swansea City. Including his final two such matches in charge of Paris Saint-Germain, Tuchel has gone six games without conceding at home in league competition.
Sheffield United 0-2 Liverpool: Klopp's men get back on track
After four consecutive top-flight defeats champions Liverpool got their top-four bid back on track at Bramall Lane.
Curtis Jones opened the scoring with his second goal for the Reds. In doing so, he became the youngest Liverpool player (20 years and 29 days) to score an away Premier League goal since Raheem Sterling in December 2014 against Burnley (20y 18d).
Their second – an own goal by Kean Bryan – was their 7,000th in the English top-flight, becoming only the second team to reach that tally after Merseyside rivals Everton (7,108).
Adrian was in goal for Jurgen Klopp's men and the Spaniard has now been on the winning side in 10 of his 12 Premier League starts for the club, although this was only his third clean sheet.
The Blades, meanwhile, have now lost 21 games this season. They are the first side since Newport County in the fourth tier in 1970-71 to lose as many as 21 of their first 26 matches in an English Football League season.
Tottenham 4-0 Burnley: Brilliant Bale torments sorry Clarets
Bale was at his best as Tottenham registered their biggest Premier League home win since they thumped the Clarets 5-0 in December 2019.
His first came after just 68 seconds, which was the fastest goal Burnley have ever conceded in a Premier League match. The previous quickest was a Yerry Mina effort after 99 seconds for Everton in December 2018.
Harry Kane doubled Spurs' advantage to continue his fine run against Sean Dyche's side. No player has scored more Premier League goals against Burnley than Kane (eight, level with Riyad Mahrez), with the England striker involved in 10 goals in his last six league appearances against them (seven goals, three assists).
Lucas Moura added a third before Bale wrapped up the scoring to take his goal involvements to seven in his last four appearances in all competitions.
At the back, Hugo Lloris celebrated his 100th clean sheet in the competition. He became the 16th goalkeeper to reach that landmark, while he is the ninth quickest to reach it (285 games).
Burnley, meanwhile, have now lost 12 of their last 15 away top-flight matches against Spurs, shipping 48 goals and conceding at least four goals in seven games.
Leicester City 1-3 Arsenal: Gunners storm back to end 'top three' hoodoo
Arsenal ended a four-game winless run against the Foxes in the Premier League, securing their first victory against them in the competition since October 2018.
It started poorly for Mikel Arteta's side, though, with Youri Tielemans scoring his sixth goal of the season early on. That is as many as he had scored in his first two seasons at the club combined.
David Luiz pulled the Gunners level before Alexandre Lacazette put them ahead from the penalty spot. The France international has converted all five of his penalties for Arsenal across all competitions, while only Pierre-Emerick Aubameyang (13) has now netted more goals for the Gunners than Lacazette (11) this term.
Nicolas Pepe sealed the three points and has now equalled his Premier League goal tally from last season, scoring five this campaign in 13 fewer appearances (18 this term, 31 last season).
The result marked Arsenal's first away victory against a team starting the day in the top three of the Premier League since January 2015 (2-0 v Manchester City) – they were winless in their last 14 such games ahead of this clash (D3 L11).
Crystal Palace 0-0 Fulham: Lucky Eagles escape with a point
It should come as no surprise that this game ended goalless given Fulham's penchant for draws this season.
Just one of the Cottagers' first 21 Premier League games under Scott Parker ended level, but the stalemate at Selhurst Park was their 10th draw in their last 15 top-flight matches.
They were comfortably the better side and attempted 16 shots. Fourteen of those came in the second period – the most they have had in the final 45 minutes of a Premier League away game since 2003-04 without scoring.
Palace, meanwhile, have somehow managed to pick up four points from their last two league games despite attempting just six shots (facing 41), having only nine touches in the opposition box (compared to 70 by their opponents), and completing just 442 passes (compared to their opponents' 1065).
Indeed, they managed just 33 attempts in their five Premier League matches in February – the lowest recorded by a team in a single month of at least five games since the start of the 2003-04 campaign.