Tottenham go in search of a rare Premier League win at Chelsea on Sunday on a high from a stunning victory at Leicester City and David Moyes could return to haunt Manchester United.
Steven Bergwijn scored twice deep into stoppage time as Spurs snatched a 3-2 win at the King Power Stadium on Wednesday, moving above Arsenal into fifth place.
Tottenham have a poor Premier League record at Stamford Bridge, but the European champions have picked up only three points from four Premier League matches.
Moyes takes his fourth-placed West Ham side to his former club on Saturday for a clash between two Champions League hopefuls, while second-placed Liverpool head to Crystal Palace on Sunday.
Leaders Manchester City are on the road at Southampton and struggling Newcastle United do battle with Leeds United at Elland Road.
Whet the appetite for this weekend's standout fixtures by testing your knowledge with Stats Perform's Opta-powered quiz. See if your memory serves you right by checking the answers at the bottom of the page.
1. Spurs have won just one of their past 31 away games against Chelsea in the league. Which player scored twice in that solitary 3-1 victory in April 2018?
2. Moyes has never won an away Premier League match against the Red Devils in 14 attempts (D4 L10). Who is the only manager in the Premier League era to have failed to win at United in more top-flight games?
3. Which two Liverpool players helped themselves to a brace in a stunning 7-0 rout of Palace at Selhurst Park last season?
4. Southampton have won their last two Premier League home games against sides starting the day top of the table. Who were those two sides at the summit when they were beaten by Saints last season?
5. Newcastle have won just one of their 20 Premier League matches this season. Only one of the last 12 sides to have one won one of their opening 20 top-flight games in a season has survived relegation, can you name them?
1. Dele Alli
2. Harry Redknapp (15)
3. Mohamed Salah and Roberto Firmino
4. Liverpool and Everton
5. West Brom (2004-05)