England will be without Joe Marler when they face Australia at Twickenham on Saturday after the prop tested positive for coronavirus.
Marler returned a positive lateral flow test on Monday and immediately went into isolation.
The 31-year-old will isolate for 10 days after a PCR test confirmed he has contracted COVID-19.
All of the other England players and staff returned negative lateral flow tests, with additional PCR test results not yet received.
Owen Farrell rejoined the squad on Monday after he missed the 69-3 hammering of Tonga on Saturday, having tested positive for coronavirus last week.
Marler came off the bench in that thrashing at Twickenham, but will play no part against the Wallabies.
He will hope to be available to return when Eddie Jones' side take on world champions South Africa on November 20.
