Celtics rookie forward Jayson Tatum left Wednesday's 107-96 win over the Lakers early with a right ankle injury and did not return.
Tatum scored five points in just nine minutes of action. After the game, he was seen sporting a walking boot for precautionary reasons.
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Boston has dealt with a myriad of key injuries already this season. Gordon Hayward was lost for the season in the first quarter of the first game, and Al Horford missed Wednesday's game with a concussion.
The Celtics (10-2) have won 10 straight games, but they may be running on fumes now with so many key players out of the lineup.