Isco remains on the sidelines after Real Madrid named a 20-man squad for Wednesday's Copa del Rey semi-final showdown with Barcelona.
The Spain playmaker has found himself out of favour since Santiago Solari took charge at the Santiago Bernabeu.
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He was an unused substitute when the first leg finished 1-1 at Camp Nou on February 6. He was then out due to a back complaint but returned to training last week.
The main source of intrigue over the Madrid line-up concerns who will start at left-back.
Our 20-man squad for tonight's #RMClasico! #RMCopa pic.twitter.com/vEQN27vfsJ
— Real Madrid C.F. (@realmadriden) February 27, 2019
Brazil star Marcelo played in the first leg but once again found himself left among the substitutes to the benefit of Sergio Reguilon during Sunday's 2-1 win at Levante.
The 22-year-old defender has enjoyed a breakthrough campaign under Solari, starting six of Los Blancos' past seven games in LaLiga.