Anthony Joshua will defend his WBA, WBO and IBF heavyweight titles against former undisputed cruiserweight champion Oleksandr Usyk at Tottenham Hotspur Stadium on September 25.
Joshua had been in negotiations to face Tyson Fury in an all-British blockbuster but an arbitration hearing ruled Deontay Wilder had a contractual right to face the WBC champion for a third time.
Fury and Wilder's trilogy showdown was set to take place this weekend before the 'Gypsy King' tested positive for coronavirus.
That bout has now been shifted to October 9 in Las Vegas, meaning Joshua will have another chance to impress before his heavyweight rivals step out again.
That is not to say looking ahead to future contests would be wise for the 31-year-old, given the exceptionally skilled Usyk is intent on cleaning up at heavyweight as he did in the 200lbs division and boasts a professional record of 18 victories and no defeats.
September 25th I will step down from my throne to engage in battle pic.twitter.com/YIYcqNywuQ— Anthony Joshua (@anthonyjoshua) July 20, 2021
Joshua avenged his shock loss to Andy Ruiz with a lopsided points win over the Mexican-American in Saudi Arabia at the end of 2019. The sole defence of his second reign as champion came with a dominant ninth-round stoppage of Kubrat Pulev at Wembley Arena last December, before Joshua's latest period of Fury-based frustration began.
Usyk has previously enjoyed success in the UK, both when he knocked out Tony Bellew in his final fight at cruiserweight and outpointed the veteran Dereck Chisora last year.
The Ukrainian also won heavyweight gold at London 2012, where Joshua triumphed at super-heavyweight. Indeed, this will be the first professional meeting between men who won Olympic gold medals in those respective categories.
"We are two Olympic gold medallists who have fought our way to the top and never avoided challenges," Joshua said.
"The stadium is exceptional, the atmosphere will be electric. I'm honoured to be the first person to fight in such an awe-inspiring venue. The stage is set and I am ready to handle business."
Joshua's stadium shows have become a fixture of UK boxing in the modern era.
He stopped Wladimir Klitschko in a thrilling Wembley contest in April 2017 before a September 2018 KO of Alexander Povetkin at the same venue – a fight for which Usyk was in attendance.
In between those triumphs, he beat Carlos Takam and then-WBO champion Joseph Parker at Cardiff's Principality Stadium.
In his sole remarks around the fight announcement, Usyk cryptically said: "The path will be mastered by the walking one."