England seamer Stuart Broad will miss the remainder of the Test series against India after tearing his right calf.
Broad suffered the injury during the warm-up in training on Tuesday and will play no further part in the five-match series.
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England called up Saqib Mahmood as cover on Wednesday, with James Anderson also set to miss the second Test at Lord's this week after struggling with a tight thigh.
An England and Wales Cricket Board (ECB) statement read: "England seamer Stuart Broad has sustained a tear to his right calf and has been ruled out of the Test series against India.
"He underwent an MRI scan in London on Wednesday lunchtime, which revealed a tear."
Mahmood could be set to make his Test debut on Thursday in the absence of England's vastly experienced new-ball pairing of Broad and Anderson.
Pace duo Mark Wood and Craig Overton are also pushing for recalls, while off-spinning all-rounder Moeen Ali was added to the squad this week following a first Test that ended in a draw at Trent Bridge.
