Australian Open: 'Nights like this mean everything' – Nadal

Nadal cruised into a two-set lead against Karen Khachanov on Friday, though the Spaniard had to overcome a third-set fightback to win 6-3 6-2 3-6 6-1.

The 35-year-old - who triumphed at the Melbourne Summer Set earlier in January - has won all six of the matches he has played so far in 2022.

Nadal has endured a difficult time with injuries in recent seasons but, with Novak Djokovic out of the picture after his deportation from Australia this week, he has a record 21st grand slam triumph firmly in his sights.

"It is a very special week for me, coming back," said Nadal, who was out of action from August until December, when he played in an exhibition event in Dubai.

"Every single time I am able to play here is very special. I played against a great player and a good friend on Tour. It was my best match since I have come back without a doubt.

— #AusOpen (@AustralianOpen) January 21, 2022

"I have gone through some very tough times over the past year, but nights like tonight mean everything.

"I keep fighting and going every day. I put a lot of effort in to be back with where I am today, so I am happy."

Nadal has won all eight matches against Russian Khachanov, and he will face Adrian Mannarino, whose four-set win over Aslan Karatsev concluded late into the Melbourne night.