Massimiliano Allegri confirmed Paulo Dybala and Alvaro Morata will miss Juventus' Champions League clash with Chelsea following injuries suffered against Sampdoria.
The Bianconeri's second successive Serie A win came at a cost as both Dybala and Morata were ruled out of their Group H showdown with the reigning European champions.
Dybala was on target with the opening goal as Juve moved up to ninth in Serie A, eight points behind leaders Milan, with a 3-2 defeat of Sampdoria.
Yet Allegri did not appear overly concerned by the absence of the two forwards.
"We'll see how to play against Chelsea without Dybala and Morata," he said.
"It's not a decisive game anyway. The key games for the qualification are those against Zenit."
Manuel Locatelli told DAZN of Dybala's injury: "I hope it's nothing serious. He is our great champion and we hope he'll be back as soon as possible."
It was an unconvincing win for a Juve team who have not looked like title contenders in the first season of Allegri's second spell in charge.
Leonardo Bonucci's penalty doubled their lead before Maya Yoshida pulled one back prior to half-time.
Locatelli restored Juve's two-goal lead but Antonio Candreva's 83rd-minute goal set up a tense finish.
"We are all responsible, we all know what we have to do on the field and to help each other out. The fundamental thing today was to win," Locatelli said.
"What happens in the locker room stays there, we listen to what the coach says and must get our way back up the table."
