Sergio Aguero is not in the Manchester City squad to face Bournemouth amid reports Pep Guardiola has opted to rest his top scorer.
Aguero had started every top-flight match for the reigning champions this season and leads the Premier League goal charts with eight.
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Gabriel Jesus start up front for City in the Argentina striker's absence, with midfield duo Ilkay Gundogan and Bernardo Silva also back from short injury absences.
Danilo, who scored in the corresponding fixture last season, makes his first Premier League appearance for City this season in a defence where Nicolas Otamendi replaces John Stones at centre-back.
Five changes from Lyon as Pep shuffles the pack for #MCIBOU.
— Manchester City (@ManCity) December 1, 2018
Plus... @BernardoCSilva
IS BACK!
What's your take on the team? pic.twitter.com/bXWDCLJsUj
For Bournemouth, Andrew Surman, Lewis Cook and Tyrone Mings start in place of Dan Gosling, David Brooks and the suspended Jefferson Lerma.