March 9 (Reuters) - Manchester City will welcome Liverpool in the FA Cup quarter-finals, while Premier League leaders Arsenal travel to second-tier side Southampton following Monday’s draw.

Pep Guardiola's City secured their last-eight spot with a 3-1 victory at Newcastle United on Saturday, while Liverpool progressed with a 3-1 win at Wolverhampton Wanderers.

City have reached the quarter‑finals for the eighth consecutive season and remain on track ‌for a fourth successive FA Cup final appearance as they chase an elusive quadruple.

Record 14-times FA Cup winners Arsenal visit Southampton as Mikel Arteta’s side also bid for a quadruple having, like City, reached the League Cup final and Champions League last 16.

Third-tier bottom side Port Vale pulled off the shock of the fifth round on Sunday by beating Premier League visitors Sunderland 1-0 but face a big challenge at Chelsea, who put out hosts Wrexham in a 4-2 extra-time thriller on Saturday.

Leeds United visit West Ham United after the London side earned a shootout victory over visitors Brentford on Monday. West Ham's Konstantinos Mavropanos converted the decisive spot kick to seal a 5-3 win following a 2-2 draw after extra time.

Quarter-final draw:

Southampton v Arsenal

Chelsea v Port Vale

Manchester City v Liverpool

West Ham United v Leeds United

Matches will take place over the weekend of April 4-5.

(Reporting by Tommy Lund in Gdansk; Editing by Ken Ferris)