Inter Milan forward Lautaro Martinez has suffered a fresh calf muscle injury just days after returning from a long-term absence, the Serie A leaders said on Friday.
Argentina international Martinez's condition will be reassessed in the coming days, the club said.
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Italian media suggested the 28-year-old is expected to be sidelined for around two weeks and is set to miss Inter's matches at Como on Sunday and home to Cagliari next Friday.
Inter have a seven-point advantage over Napoli with seven rounds of the season remaining.
The injury is a blow for the Inter captain, who returned on Sunday following a six-week lay-off with a similar problem.
He scored twice in Inter's 5-2 home victory over AS Roma, taking his season tally to 16 league goals, extending his lead at the top of the Serie A scoring charts.
The injury is also a worry for Argentina as they prepare for the World Cup, with Martinez being a key part of the team that qualified for this year's tournament in North America.
