Tsitsipas to face Murray at US Open, Barty starts against Zvonareva

Stefanos Tsitsipas faces Andy Murray and Ash Barty will take on 2010 finalist Vera Zvonareva in the first round of the US Open.

French Open runner-up Tsitsipas and 2012 champion Murray is one of the standout matches in the opening round at Flushing Meadows.

Top seed Novak Djokovic will start his quest for a calendar Grand Slam against a qualifier in New York and could face a repeat of the Wimbledon final versus Matteo Berrettini in the last eight.

World number one Djokovic, a strong favourite for a record 21st major title with Rafael Nadal and Roger Federer absent due to injury, could do battle with Alexander Zverev at the semi-final stage.

@DjokerNole's road to a fourth #USOpen title Round 1: Qualifier Round 2: Struff Round 3: Goffin Round 4: De Minaur Quarterfinals: Berrettini Semifinals: Zverev Final: Medvedev pic.twitter.com/9Rtq4lPfwQ

— US Open Tennis (@usopen) August 26, 2021

Daniil Medvedev, the second seed, is in the bottom half with Tsitsipas, who he could come up against in the semi-final. Medvedev's first test will come against Frenchman Richard Gasquet.

Barty could come up against Iga Swiatek in the last eight and Karolina Pliskova if she makes it through to the semi-finals.

Simona Halep's encounter with Camila Giorgi is a mouthwatering first-round match, while defending champion Naomi Osaka returns to grand slam action against former US Open junior champion Marie Bouzkova.

Angelique Kerber could be a tough fourth round opponent for Osaka. Close friends Madison Keys and Sloane Stephens meet in another eye-catching first-round match.

There will be no Serena or Venus Williams at the final major of the year due to injuries.

@ashbarty's route to a third Grand Slam singles title Round 1: Zvonareva Round 2: Tauson Round 3: Kudermetova Round 4: Brady Quarterfinals: Swiatek Semifinals: Pliskova Final: Sabalenka#USOpen pic.twitter.com/eDo907HpX4

— US Open Tennis (@usopen) August 26, 2021