Rory Sutherland has been promoted to the British and Irish Lions starting line-up to face South Africa in the first Test after Wyn Jones was ruled out with a minor shoulder injury.
Scotland prop Sutherland was given a late call to come into the side for Saturday's showdown at Cape Town Stadium in the absence of Jones, who is expected to return to training next week.
England front-rower Mako Vunipola replaces Sutherland on the bench.
Lions head coach Warren Gatland said: "It's really bad luck for Wyn and we all feel for him missing out on tonight's game.
"However, we're confident he'll be back in training next week and have no plans to bring in anyone else at this stage."
British and Irish Lions: Stuart Hogg, Anthony Watson, Elliot Daly, Robbie Henshaw, Duhan van der Merwe, Dan Biggar, Ali Price; Rory Sutherland, Luke Cowan-Dickie, Tadhg Furlong, Maro Itoje, Alun Wyn Jones (captain), Courtney Lawes, Tom Curry, Jack Conan.
Replacements: Ken Owens, Mako Vunipola, Kyle Sinckler, Tadhg Beirne, Hamish Watson, Conor Murray, Owen Farrell, Liam Williams.