The Hurricanes made it four wins from five in Super Rugby Trans-Tasman as they defeated a luckless Reds 43-14 in Wellington on Friday.

There were just three points separating the sides approaching the hour mark before the Hurricanes made the most of clinical scoring and good fortune to ease to victory.

The Reds had nearly 60 per cent of the possession and 637 carries to their opponents' 564 but saw crucial moments go against them as they suffered a fourth defeat in five games.

Hurricanes centre Ngani Laumape's try opened the scoring but Tate McDermott's converted score levelled the contest after Tyrel Lomax had been sin-binned for a high tackle.

Jordie Barrett's penalty gave the 14-man Hurricanes a 10-7 lead at half-time before the Reds lost Filipo Daugunu to a contentious yellow card, with Ruben Love touching down soon after.

Brandon Paenga-Amosa powered over after some intense forward pressure but Dane Cole's try following a soft lineout began the Hurricanes' late surge.

Laumape was awarded a penalty try after he and Bryce Hegarty chased a kick, the referee showing the latter yellow after ruling he had deliberately hit the ball over the line to prevent a score.

Replacement Devan Flanders and a second from Coles in the final nine minutes further punished the men from Queensland.

The Highlanders secured what could be an important 33-12 bonus-point win over the Brumbies that boosted their play-off hopes.

Aaron Smith scored two tries and assisted two more in a match in which the Highlanders scored 19 unanswered points in the second half.

Len Ikitau broke the deadlock for the Brumbies but Smith, Ash Dixon and Billy Harmon put the visitors in control in Canberra, despite Lachlan Lonergan also going over.

Patelesio Tomkinson got the crucial fifth try as the Highlanders held off some late pressure to make it five wins from five ahead of the final day of home-and-away matches.