Oklahoma City Thunder big man Chet Holmgren, the second overall pick of this year's draft, will miss the entire 2022-23 season with a Lisfranc injury sustained in his right foot.

Holmgren suffered the injury in the CrawsOver Pro-Am event on Saturday in Seattle while slipping on the court defending LeBron James.

The game Holmgren was injured in ended up being cancelled because of a slippery court caused by humid conditions combined with a large crowd at the Seattle gym.

"Certainly, we are disappointed for Chet, especially given the excitement he had about getting on the floor with his teammates this season," Thunder executive vice president and general manager Sam Presti said in a statement. "We know Chet has a long career ahead of him within our organisation and the Oklahoma City community."

Holmgren and James were a part of a handful of NBA players in the pro-am along with Jayson Tatum, Dejounte Murray, Aaron Gordon and the only player selected ahead of Holmgren in this year's draft, Paolo Banchero.

The Thunder drafted Holmgren after he averaged 14.1 points, 9.9 rebounds and 3.7 blocks in 32 games in his lone collegiate season for Gonzaga in 2021-22.

Not only an excellent rim-protector on defense, Holmgren was a solid perimeter shooter for his size, knocking down 39.0 per cent of his three-point attempts.

Despite his thin stature, Holmgren did not appear to have any trouble making the transition to the pro game, averaging 14 points and 8.4 rebounds in five games for the Thunder at the Las Vegas Summer League.

"One of the things that most impressed us during the process of selecting Chet was his determination and focus," Presti said. "We expect that same tenacity will carry him through this period of time as we work together and support him during his rehabilitation."