Amir Khan will face Colombian Samuel Vargas at Arena Birmingham in the second fight of his comeback on September 8.
Khan took just 40 seconds to knock out Phil Lo Greco on his return to the ring in April following an absence of almost two years.
The former unified super-lightweight world champion is eyeing welterweight titles further down the line and he will be aiming to make another statement against a 29-year-old who is ranked 10th by the WBA.
Khan's old rival Danny Garcia and IBF champion Errol Spence Jr both knocked out Garcia and the Brit is planning to put on another devastating show.
"One of my aims this year was to be as active as possible so I'm very happy to be back in the ring again so soon against Samuel Vargas," said Khan.
"Vargas is a tough and well-schooled fighter who has shared the ring with some top welterweights including Danny Garcia and Errol Spence Jr.
"I have to get past Vargas before looking at the biggest challenges going forward. I'm not going to be taking Vargas lightly because I know he will be coming with everything on September 8.
"I hope to give the fans in Birmingham the same excitement and fireworks as my last fight. It will be one not to miss."
Vargas, who is based in Lo Greco's home city of Toronto, warned: "I have been granted more than enough time to properly prepare for Amir and you will see the best Samuel Vargas to date.
"Mark my words, we might both be from the same city and county but I am nothing like Phil Lo Greco that's a guarantee – I’m going to give Amir hell."