Three of the top seeds in the Miami Open field were eliminated on Monday as Felix Auger-Aliassime, Hubert Hurkacz and Frances Tiafoe were all sent packing.

Fifth seed Auger-Aliassime was taken out 6-2 7-5 in one of the biggest wins of Francisco Cerundolo's career, with the Argentine avenging recent losses to the Canadian at both the Australian Open and the Indian Wells Open.

Adrian Mannarino's 7-6 (7-5) 7-6 (7-0) victory over eighth seed Hurkacz was arguably an even bigger upset, as it snapped his streak of nine consecutive losses against top-10 opponents at Masters 1000 events.

The 34-year-old Frenchman absorbed 20 aces from Hurkacz and still came out on top, limiting his own unforced errors to 13 for the match.

A third upset of the day saw unseeded Italian Lorenzo Sonego play a near faultless match to eliminate 12th seed Tiafoe, finishing the contest with 22 winners and only two unforced errors, while not facing a single break point in the brief 68-minute battle.

There was no drama for Daniil Medvedev as the fourth seed received a walkover against Alex Molcan, and he will face France's Quentin Halys in the fourth round after his 7-6 (7-2) 6-3 triumph over Mackenzie McDonald.

Two seed Stefanos Tsitsipas almost joined the long list of seeded victims, but he prevailed 6-3 4-6 6-4 against Christian Garin in the day's only three-setter.

The Greek star will meet Russian 14th seed Karen Khachanov in the fourth round after his comfortable 6-2 6-4 result over Jiri Lehecka, while unseeded American Christopher Eubanks finished the day's play with a 6-3 7-6 (9-7) defeat of Gregoire Barrere.