Daniil Medvedev crashed out of the French Open in straight sets to Marin Cilic, who hailed the victory as one of the best of his career after producing a scintillating display on Court Philippe-Chatrier.

Second seed Medvedev was blown away 6-2 6-3 6-2 in just one hour and 45 minutes, with the 33-year-old Cilic not looking back after forcing successive breaks to wrap up the first set.

Having broken Medvedev's serve six games into the opener, the 2014 US Open champion did likewise en route to clinching the second set, with Cilic winning 90 per cent of first-serve points over the course of a dominant display.

If Medvedev still harboured hopes of a comeback at that point, they were swiftly dashed in the third set as Cilic maintained his relentless pace, breaking the world number two in each of his first two service games as he went on to record his first career win over the Russian.

Medvedev failed to force a single break point during a miserable outing under the floodlights, with the near-flawless Cilic not registering a single double fault as he reached his first grand slam quarter-final since the 2018 US Open.

Speaking on court after teeing up a last-eight meeting with Andrey Rublev, Cilic said the win was one of the best of his career.

"It was an absolutely fantastic match, from the first point until the last. I enjoyed the atmosphere, I enjoy the night sessions here," he said.

"I played incredible tennis, one of the best matches of my career, from start to finish, and I just enjoyed being here.

"We only have one opportunity to play this sport so I try to always give my best, even when things don't go my way.

"When you're working hard and when you're really persistent, really consistent with your training, good things come. It's a great feeling to be playing again like this."