Tom Curry will play no further part in England's tour of Australia after he was ruled out for the remaining two games through concussion.
The Sale Sharks flanker started for Eddie Jones' side in Saturday's first Test in Perth, but was replaced by Lewis Ludlam at the half-time break as the Wallabies snapped their losing streak in a dramatic 30-28 fightback win.
Curry had travelled to Brisbane for the tourists' next match, but will now fly back to England later this week in what is a sizeable blow.
The 24-year-old - a member of the British and Irish Lions party that toured South Africa last year - is considered a frontrunner for Jones' squad at the 2023 Rugby World Cup in France.
"It has been agreed that in the interest of player welfare and recovery, [Curry] will take no further part in the tour," the Rugby Football Union confirmed in a brief statement.
It is not yet known whether England will call up a replacement for Curry, who is the first noticeable injury the tourists have had to deal with.
The Sharks star - a Premiership Cup winner with the club in 2020, a year on from playing in England's World Cup final defeat to the Springboks in Japan - will continue further assessment upon his return to England.