North Carolina have set up a tantalising Final Four matchup with historic rivals Duke after ending the 'Cinderella' run of the 15-seed Saint Peter's Peacocks.

The Peacocks assumed the role of this year's loveable underdogs of March Madness when they became the first 15 seed to make it through to the Elite Eight, but they were no match for North Carolina, going down 69-49 in a game that was never close.

Armando Bacot was the star of the show for the Tar Heels, finishing with 20 points on eight-of-15 shooting to go with a monstrous 22 rebounds.

With the win, North Carolina booked their spot against Duke in the Final Four as Duke head coach Mike Krzyzewski searches for his sixth national title in his 42nd and final year in charge.

One of the fiercest rivalries in American sports, North Carolina and Duke have played 256 times since their first meeting in 1920, but incredibly have never met in the NCAA Tournament.

We love you coach #CarolinaFamily | #MarchMadness pic.twitter.com/1c8lnzdD2m
— Carolina Basketball (@UNC_Basketball) March 27, 2022

Earlier in the day, it was a tale of two halves as one-seed Kansas took on 10-seed Miami, with the higher-ranked Jayhawks struggling out of the gate to trail 35-29 at half-time.

Kansas shot zero-for-five from long range and three-for-nine from the free throw line in the first half but flipped a switch in the second half, showing why they are considered one of the favourites to win the tournament.

The second half was total domination, out-scoring the Hurricanes 47-15 in the 20 minutes to pull away for an easy 76-50 win.

The top performance in the game came from the top NBA prospect, Kansas' Ochai Agbaji, who finished with 18 points on eight-of-12 shooting, including two-from-two from long range. He also registered five rebounds, four assists and four steals as he continues to build his case as a potential lottery pick in this year's NBA Draft.