Wesley Fofana has been denied a Six Nations farewell in France's match against Italy on Saturday due to injury.

Clermont Auvergne centre Fofana reportedly sustained an injury during training on Friday and has been replaced in the starting XV by Geoffrey Doumayrou.

The 31-year-old, who will retire from international rugby after this year's World Cup, started Les Bleus' opening 24-19 defeat against Wales but has not featured in the Six Nations since.

France will hope to round off a disappointing campaign with a win in Rome as they look to beat Scotland to fourth place, with Italy already consigned to the wooden spoon.

Blessé, @wesleyfofana doit déclarer forfait. C'est @doumgeof qui le remplace dans le XV de départ. Voici la nouvelle composition des Bleus pour ce match contre l'Italie. Coup d'envoi à 13h30 sur @France2tv #ITAFRA #XVdeFrance #NeFaisonsXV pic.twitter.com/hoB8T5OMVv

— Fédération Française de Rugby (@FFRugby) March 16, 2019