Ollie Watkins could make history for Aston Villa when the in-form striker faces Everton this weekend and James Ward-Prowse has a David Beckham record in his sights.
Watkins has been on fire since the World Cup and the relegation-threatened Toffees will have to be on their guard when he leads the line at Goodison Park on Saturday.
Ward-Prowse gave Southampton a precious victory at Chelsea last weekend and will attempt to inspire another win in a huge battle between the bottom two away to Leeds United.
As struggling Saints and Leeds go in search of precious points, you might need to shake your fantasy team up in order to start climbing the table.
Using Opta data, Stats Perform suggest four men who can ensure you have a profitable weekend.
Kenny Tete (Wolves v Fulham)
Fulham full-back Tete would probably not have been on a list of potential fantasy picks at the start of the season, but he really ought to be now.
The Cottagers have kept five clean sheets since the World Cup and Tete has played the entire match in all but one of those games.
Andy Robertson (five) is the only defender to have provided more assists in the top flight than Tete's four this season and Wolves will have to keep an eye on him marauding forward down the right wing on Friday.
Oleksandr Zinchenko (Leicester City v Arsenal)
Left-back Zinchenko scored his first Premier League goal to draw Arsenal level for a second time before they won 4-2 at Villa last Saturday.
The Ukraine international has become a popular figure since joining the Gunners from Manchester City, making an impact at both ends of the field.
Zinchenko has created an average of 0.71 chances per 90 minutes in leaders' Arsenal's quest to win the title and could be influential when they travel to take on Leicester City.
Forever making memories pic.twitter.com/hgNl3DMIF8— Arsenal (@Arsenal) February 20, 2023
James Ward-Prowse (Leeds United v Southampton)
If Southampton are to avoid relegation to the Championship, captain Ward-Prowse must continue to step up.
He gave another demonstration of his free-kick prowess by earning managerless Saints a brilliant win at toothless Chelsea last Saturday.
That moved him one short of Beckham's Premier League record tally of scoring 18 direct free-kicks and it would be no great surprise if he goes level with the former England captain in a crunch clash at Elland Road.
Only Marcus Rashford (10) and Erling Haaland (eight) have scored more goals since the World Cup than the Saints skipper's five, so you might want to get him in your midfield.
Ollie Watkins (Everton v Aston Villa)
Another man who has been outstanding in 2023 is Watkins, who is loving life under Unai Emery at Villa.
The striker could become the first Villa player to find the back of the net in five consecutive Premier League games when they do battle with lowly Everton.
He has scored five of his seven top-flight goals this season since the World Cup and can keep his streak going at Goodison Park.