Tottenham boss Jose Mourinho expects striker Harry Kane to face a lengthy spell on the sidelines with a hamstring injury.
The England captain suffered the blow in the defeat at Southampton on New Year's Day, when he had to be substituted in the second half.
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Final results on the seriousness of the injury have yet to reach Mourinho, but he cannot see a scenario where it would be positive.
"Maybe later today we have news, but if you ask me my feeling, good news or bad news, I am more on bad news than good news," Mourinho said on Friday.
"Kane leaving a match the way he did it, he didn’t think twice, it took him two seconds to realise the severity of his situation."
TEAM NEWS:
— Tottenham Hotspur (@SpursOfficial) January 3, 2020
Heung-Min Son (suspension) – available after completing three-match ban.
@ericdier (illness) & @KWPeters (calf) – returned to training.#THFC #COYS pic.twitter.com/BNwn4W3NPl
Record signing Tanguy Ndombele also came off against Southampton, with a hip injury his problem.
Like Kane, Ndombele will miss the FA Cup third-round match at Middlesbrough on Sunday.
Midfielder Eric Dier could return after recovering from a virus, while forward Son Heung-min has completed a suspension.