Davide Calabria suffered a broken leg during AC Milan's Coppa Italia defeat to Lazio, the club have confirmed.
The 22-year-old took a heavy blow to his left leg and tests have shown he has a compound fracture of his fibula.
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Initial reports in Italy suggest Calabria will need approximately two months to recover, meaning his season is over.
The full-back has made 33 appearances in all competitions this season, scoring one goal.
Milan were beaten 1-0 in Wednesday's second leg, Joaquin Correa's goal enough to settle the two-legged tie in Lazio's favour.
Immediately back to work: Attentions turn to #TorinoMilan
— AC Milan (@acmilan) April 25, 2019
Subito al lavoro a Milanello: testa al Toro pic.twitter.com/blAeE7WsyL